Publications 2010 - 2001

2010

Linda Y Sender, Kathrin Gibbert, Yasemin Suezer, Heinfried H Radeke, Ulrich Kalinke, Zoe Waibler: CD40 ligand-triggered human dendritic cells mount interleukin-23 responses that are further enhanced by danger signals. Molecular Immunology 03/2010; 47(6):1255-61., DOI:10.1016/j.molimm.2009.12.008

Ralf J Ludwig, Peri Bergmann, Jurate Garbaraviciene, Esther von Stebut, Heinfried H Radeke, Jens Gille, Sandra Diehl, Katja Hardt, Reinhard Henschler, Roland Kaufmann, Josef M Pfeilschifter, Wolf-Henning Boehncke: Platelet, Not Endothelial, P-Selectin Expression Contributes to Generation of Immunity in Cutaneous Contact Hypersensitivity. American Journal Of Pathology 03/2010; 176(3):1339-45., DOI:10.2353/ajpath.2010.081100

2009

Ralf J Ludwig, Katja Hardt, Max Hatting, Roxana Bistrian, Sandra Diehl, Heinfried H Radeke, Maurizio Podda, Michael P Schön, Roland Kaufmann, Reinhard Henschler, Josef M Pfeilschifter, Sentot Santoso, Wolf-Henning Boehncke: Junctional adhesion molecule (JAM)-B supports lymphocyte rolling and adhesion through interaction with alpha4beta1 integrin. Immunology 10/2009; 128(2):196-205., DOI:10.1111/j.1365-2567.2009.03100.x

Melanie Koenig, Sabine Huenecke, E Salzmann-Manrique, Ruth Esser, R Quaritsch, Dieter Steinhilber, Heinfried H. Radeke, Hans Martin, Peter Bader, Thomas Klingebiel, Dieter Schwabe, G Schneider, T Lehrnbecher, Andreas Orth, Ulrike Koehl: Multivariate analyses of immune reconstitution in children after allo-SCT: Risk-estimation based on age-matched leukocyte sub-populations. Bone marrow transplantation 08/2009; 45(4):613-21., DOI:10.1038/bmt.2009.204

Cornelia Richter, Martina Herrero San Juan, Jutta Will, Ralf P Brandes, Ulrich Kalinke, Shizuo Akira, Josef M Pfeilschifter, Malin Hultqvist, Rikard Holmdahl, Heinfried H Radeke: Ncf1 Provides a Reactive Oxygen Species-Independent Negative Feedback Regulation of TLR9-Induced IL-12p70 in Murine Dendritic Cells. The Journal of Immunology 05/2009; 182(7):4183-91., DOI:10.4049/jimmunol.0800795

Susanne Alban, Ralf J Ludwig, Gerd Bendas, Michael P Schön, Gertie J Oostingh, Heinfried H Radeke, Juliane Fritzsche, Josef Pfeilschifter, Roland Kaufmann, Wolf-Henning Boehncke: PS3, A Semisynthetic β-1,3-Glucan Sulfate, Diminishes Contact Hypersensitivity Responses Through Inhibition of L- and P-Selectin Functions. Journal of Investigative Dermatology 05/2009; 129(5):1192-202., DOI:10.1038/jid.2008.358

2008

Oliver Giegold, Ralf J Ludwig, Katja Hardt, Jutta Will, Michael P Schön, Gertie J Oostingh, Josef M Pfeilschifter, Wolf-Henning Boehncke, Heinfried H Radeke: Computer-aided analysis of cell interactions under dynamic flow conditions. Experimental Dermatology 11/2008; 18(3):238-45., DOI:10.1111/j.1600-0625.2008.00793.x

Anja Schramme, Mohamed Sadek Abdel-Bakky, Paul Gutwein, Nicholas Obermüller, Patrick C Baer, Ingeborg A Hauser, Andreas Ludwig, Stefan Gauer, Liliana Schäfer, Ewelina Sobkowiak, Peter Altevogt, Michael Koziolek, Eva Kiss, Hermann-Josef Gröne, Ritva Tikkanen, Itamar Goren, Heinfried Radeke, Josef Pfeilschifter: Characterization of CXCL16 and ADAM10 in the normal and transplanted kidney. Kidney International 09/2008; 74(3):328-38., DOI:10.1038/ki.2008.181

Elke Wiesemann, Milani Deb, Bernhard Hemmer, Heinfried H Radeke, Anja Windhagen: Early identification of interferon-beta responders by ex vivo testing in patients with multiple sclerosis. Clinical Immunology 07/2008; 128(3):306-13., DOI:10.1016/j.clim.2008.04.007

Anke Doller, El-Sayed Akool, Andrea Huwiler, Roswitha Müller, Heinfried H Radeke, Josef Pfeilschifter, Wolfgang Eberhardt: Posttranslational Modification of the AU-Rich Element Binding Protein HuR by Protein Kinase C Elicits Angiotensin II-Induced Stabilization and Nuclear Export of Cyclooxygenase 2 mRNA. Molecular and Cellular Biology 05/2008; 28(8):2608-25., DOI:10.1128/MCB.01530-07

Carolin Daniel, Nico A Sartory, Nadine Zahn, Heinfried H Radeke*, Jürgen M Stein*: Immune Modulatory Treatment of Trinitrobenzene Sulfonic Acid Colitis with Calcitriol Is Associated with a Change of a T Helper (Th) 1/Th17 to a Th2 and Regulatory T Cell Profile. Journal of Pharmacology and Experimental Therapeutics 02/2008; 324(1):23-33., *) two authors contributed equally. DOI:10.1124/jpet.107.127209

2007

Frank Behrens, Andrea Himsel, Stefan Rehart, Joanna Stanczyk, Björn Beutel, Stefanie Y Zimmermann, Ulrike Koehl, Burkhard Möller, Steffen Gay, Joachim P Kaltwasser, Josef M Pfeilschifter, Heinfried H Radeke: Imbalance in distribution of functional autologous regulatory T cells in rheumatoid arthritis. Annals of the Rheumatic Diseases 09/2007; 66(9):1151-6., DOI:10.1136/ard.2006.068320

Carolin Daniel, Nico A Sartory, Nadine Zahn, Ronald Schmidt, Gerd Geisslinger, Heinfried H Radeke*, Jurgen M Stein*: FTY720 ameliorates oxazolone colitis in mice by directly affecting T helper type 2 functions. Molecular Immunology 08/2007; 44(13):3305-16., *) two authors contributed equally.DOI:10.1016/j.molimm.2007.02.026

Anke Doller, Andrea Huwiler, Roswitha Müller, Heinfried H Radeke, Josef Pfeilschifter, Wolfgang Eberhardt: Protein Kinase C alpha-dependent Phosphorylation of the mRNA-stabilizing Factor HuR: Implications for Posttranscriptional Regulation of Cyclooxygenase-2. Molecular Biology of the Cell 07/2007; 18(6):2137-48., DOI:10.1091/mbc.E06-09-0850

Zoe Waibler, Ulrich Kalinke, Jutta Will, Martina Herrero San Juan, Josef M Pfeilschifter, Heinfried H Radeke: TLR-ligand stimulated interleukin-23 subunit expression and assembly is regulated differentially in murine plasmacytoid and myeloid dendritic cells. Molecular Immunology 04/2007; 44(7):1483-9., DOI:10.1016/j.molimm.2006.09.001

Elizabeth Ramos-Lopez, Patrick Brück, Thomas Jansen, Josef M Pfeilschifter, Heinfried H Radeke, Klaus Badenhoop: CYP2R1-, CYP27B1- and CYP24-mRNA expression in German type 1 diabetes patients. The Journal of Steroid Biochemistry and Molecular Biology 04/2007; 103(3-5):807-10., DOI:10.1016/j.jsbmb.2006.12.056

Carolin Daniel, Nico Sartory, Nadine Zahn, Gerd Geisslinger, Heinfried H Radeke*, Juergen M Stein*: FTY720 Ameliorates Th1-Mediated Colitis in Mice by Directly Affecting the Functional Activity of CD4+CD25+ Regulatory T Cells. The Journal of Immunology 03/2007; 178(4):2458-68., *) two authors contributed equally. DOI:10.4049/jimmunol.178.4.2458

Christina D Keller, Pilar Rivera Gil, Markus Tölle, Markus van der Giet, Jerold Chun, Heinfried H Radeke, Monika Schäfer-Korting, Burkhard Kleuser: Immunomodulator FTY720 Induces Myofibroblast Differentiation via the Lysophospholipid Receptor S1P3 and Smad3 Signaling. American Journal Of Pathology 02/2007; 170(1):281-92., DOI:10.2353/ajpath.2007.060485

2006

Simone Rubant, Ralf J. Ludwig, Jeannette Pfeffer, Petra Schulze-Johann, Roland Kaufmann, Josef M. Pfeilschifter, Wolf-Henning Boehncke, Heinfried H. Radeke: Erratum: Eukaryotic of the broad-spectrum chemokine receptor antagonist vMIP-II and its effects on T-cell function in vitro and in vivo (Experimental Dermatology (2006) vol. 15 (634-642)). DOI:10.1111/j.1600-0625.2006.00535.x

Carolin Daniel, Heinfried H Radeke, Nico A Sartory, Nadine Zahn, Ulrich Zuegel, Andreas Steinmeyer, Jürgen Stein: The New Low Calcemic Vitamin D Analog 22-Ene-25-Oxa-Vitamin D Prominently Ameliorates T Helper Cell Type 1-Mediated Colitis in Mice. Journal of Pharmacology and Experimental Therapeutics 12/2006; 319(2):622-31., DOI:10.1124/jpet.106.107599

Sabine Beck, G Beck, Thorsten Ostendorf, Juergen Floege, G Lambeau, T Nevalainen, Heinfried H Radeke, S Gurrieri, U Haas, B Thorwart, Josef Pfeilschifter, Marietta Kaszkin: Upregulation of group IB secreted phospholipase A(2) and its M-type receptor in rat ANTI-THY-1 glomerulonephritis. Kidney International 11/2006; 70(7):1251-60., DOI:10.1038/sj.ki.5001664

Simone Rubant, Ralf J Ludwig, Jeannette Pfeffer, Petra Schulze-Johann, Roland Kaufmann, Josef M Pfeilschifter, Wolf-Henning Boehncke, Heinfried H Radeke: Eukaryotic expression of the broad-spectrum chemokine receptor antagonist vMIP-II and its effects on T-cell function in vitro and in vivo. Experimental Dermatology 09/2006; 15(8):634-42., DOI:10.1111/j.1600-0625.2006.00455.x

2005

Ralf J Ludwig, Thomas M Zollner, Sentot Santoso, Katja Hardt, Jens Gille, Holger Baatz, Petra Schulze Johann, Jeannette Pfeffer, Heinfried H Radeke, Michael P Schön, Roland Kaufmann, Wolf-Henning Boehncke, Maurizio Podda: Junctional Adhesion Molecules (JAM)-B and -C Contribute to Leukocyte Extravasation to the Skin and Mediate Cutaneous Inflammation. Journal of Investigative Dermatology 11/2005; 125(5):969-76., DOI:10.1111/j.0022-202X.2005.23912.x

Heinfried H Radeke, Ralf J Ludwig, Wolf-Henning Boehncke: Experimental approaches to lymphocyte migration in dermatology in vitro and in vivo. Experimental Dermatology 10/2005; 14(9):641-66., DOI:10.1111/j.0906-6705.2005.00350.x

Ingeborg A Hauser, Sandra Spiegler, Eva Kiss, Stefan Gauer, Olaf Sichler, Ernst H Scheuermann, Hanns Ackermann, Josef M Pfeilschifter, Helmut Geiger, Hermann-Josef Gröne, Heinfried H Radeke: Prediction of Acute Renal Allograft Rejection by Urinary Monokine Induced by IFN-γ (MIG). Journal of the American Society of Nephrology 07/2005; 16(6):1849-58., DOI:10.1681/ASN.2004100836

Carolin Daniel, T Schlauch, U Zügel, A Steinmeyer, Henfried H Radeke, Dieter Steinhilber, Jürgen Stein: 22-Ene-25-oxa-vitamin D: A new vitamin D analogue with profound immunosuppressive capacities. European Journal of Clinical Investigation 06/2005; 35(5):343-9., DOI:10.1111/j.1365-2362.2005.01492.x

Heinfried H Radeke, Henrik von Wenckstern, Kirsten Stoidtner, Bettina Sauer, Stefanie Hammer, Burkhard Kleuser: Overlapping Signaling Pathways of Sphingosine 1 Phosphate and TGF-ß in the Murine Langerhans Cell Line XS52. The Journal of Immunology 04/2005; 174(5):2778-86., DOI:10.4049/jimmunol.174.5.2778

Kordula Kautz, Mario Schwarz, Heinfried H Radeke: Interference with MCP-1 gene expression by vector generated triple helix-forming RNA oligonucleotides. Cellular and Molecular Life Sciences CMLS 03/2005; 62(3):362-76., DOI:10.1007/s00018-004-4443-y

2004

Cuiyan Xin, Shuyu Ren, Burkhardt Kleuser, Soheyla Shabahang, Wolfgang Eberhardt, Heinfried Radeke, Monika Schäfer-Korting, Josef Pfeilschifter, Andrea Huwiler: Sphingosine 1-Phosphate Cross-activates the Smad Signaling Cascade and Mimics Transforming Growth Factor-beta-induced Cell Responses. Journal of Biological Chemistry 09/2004; 279(34):35255-62., DOI:10.1074/jbc.M312091200

2003

Gesine Cornelissen, H.-P. Bertelsen, Kai Lenz, Birger Hahn, Michael Schultz, Ulrich Scheffler, Elisabeth Werner, Holger Leptien, Stefan Kruess, AK Jansen, Olaf Elsholz, Toralf Gliem, B.-U. Wilhelm, Eveline Sowa, Heinfried H. Radeke, Rainer Luttman: Production of Recombinant Proteins with Pichia pastoris in Integrated Processing. Engineering in Life Sciences 09/2003; 3(9):361 - 370., DOI:10.1002/elsc.200300033

Gesine Cornelissen, H.-P. Bertelsen, Birger Hahn, Michael Schultz, Ulrich Scheffler, Elisabeth Werner, Holger Leptien, Stefan Krüß, A.-K. Jansen, Toralf Gliem, M. Hielscher, B.-U. Wilhelm, Eveline Sowa Heinfried H. Radeke, Rainer Luttmann: Herstellung rekombinanter Proteine mit Pichia pastoris in integrierter Prozessführung. Chemie Ingenieur Technik 03/2003; 75(3):281 - 290., DOI:10.1002/cite.200390058

Ulf Janssen, Eveline Sowa, Petra Marchand, Jürgen Floege, Aled O Phillips, Heinfried H Radeke: Differential Expression of Mcp-1 and Its Receptor CCR2 in Glucose Primed Human Mesangial Cells. Nephron 01/2003; 92(4):797-806., DOI:10.1159/000065448

2002

Heinfried H Radeke, Thomas Tschernig, Alexey Karulin, Georg Schumm, Steve N Emancipator, Klaus Resch, Magdalena Tary-Lehmann: CD4+ T Cells Recognizing Specific Antigen Deposited in Glomeruli Cause Glomerulonephritis-like Kidney Injury. Clinical Immunology 09/2002; 104(2):161-73., DOI:10.1006/clim.2002.5246

Heinfried H Radeke, Iska Janssen-Graalfs, Eveline N Sowa, Nelli Chouchakova, Julia Skokowa, Fabian Löscher, Reinhold E Schmidt, Peter Heeringa, J Engelbert Gessner: Opposite Regulation of Type II and III Receptors for Immunoglobulin G in Mouse Glomerular Mesangial Cells and in the Induction of Anti-glomerular Basement Membrane (GBM) Nephritis. Journal of Biological Chemistry 08/2002; 277(30):27535-44., DOI:10.1074/jbc.M200419200

Mario Schwarz, Michael Wahl, Klaus Resch, Heinfried H Radeke: IFNgamma induces functional chemokine receptor expression in human mesangial cells. Clinical & Experimental Immunology 06/2002; 128(2):285-94. DOI:10.1046/j.1365-2249.2002.01829.x